Question 1
The physician orders laboratory tests to confirm hyperthyroidism in a female client with classic signs and symptoms of this disorder. Which test result would confirm the diagnosis?
- A. No increase in the thyroid-stimulating hormone (TSH) level after 30 minutes during the TSH stimulation test
- B. A decreased TSH level
- C. An increase in the TSH level after 30 minutes during the TSH stimulation test
- D. Below-normal levels of serum triiodothyronine (T3) and serum thyroxine (T4) as detected by radioimmunoassay
Show answer and rationale
Correct answer: B — A decreased TSH level
The correct answer is B: A decreased TSH level. In hyperthyroidism, there is an overproduction of thyroid hormones, leading to a negative feedback loop that suppresses the release of TSH from the pituitary gland. Therefore, a decreased TSH level is indicative of hyperthyroidism. Rationale: 1. A: No increase in TSH level after 30 minutes during TSH stimulation test - In hyperthyroidism, the TSH level would already be low, so no increase would be expected. 2. C: An increase in TSH level after 30 minutes during TSH stimulation test - This contradicts the pathophysiology of hyperthyroidism where TSH is suppressed. 3. D: Below-normal levels of serum T3 and T4 - While low T3 and T4 levels can occur in hypothyroidism, in hyperthyroidism, there is typically an excess of these hormones. In summary, a decreased TSH