You cover cells, genetics, and life processes at the depth entrance exams actually ask. Five of the 15 questions include the correct answer and rationale. The other ten keep answers in the study hub. Continue with the HESI A2 exam guide or more HESI A2 practice questions.
Five biology questions with answers
Cover the key. Write the first action. Then open the rationale and name why the other choices fail.
Question 1
How should a researcher test the hypothesis that radiation from cell phones is significant enough to raise the temperature of water in a test tube?
A. Dial a cell phone that rests beside a test tube of water, let it ring for two minutes, and record the temperature of the water before and after the two-minute interval.
B. Dial a cell phone that rests beside a test tube of water; let it ring for two, three, and four minutes; and record the temperature of the water before and after each interval.
C. Use three different brands of cell phone; dial each as it rests beside its own test tube of water, let it ring for two minutes, and record the temperature of the water before and after the two-minute interval.
D. Use three different brands of cell phone, dial each and let one ring for two minutes, one for three minutes, and one for four minutes; record the temperature of the water before and after each interval.
Show answer and rationale
Correct answer: A — Dial a cell phone that rests beside a test tube of water, let it ring for two minutes, and record the temperature of the water before and after the two-minute interval.
To test the hypothesis that radiation from cell phones raises the temperature of water in a test tube, the most appropriate method is to dial a cell phone next to a test tube of water, let it ring for a consistent two-minute interval, and record the temperature before and after. Choice A is correct because it provides a controlled approach to isolate the impact of the phone's radiation on the water temperature. Choices B, C, and D introduce additional variables that could confound the results. Choice B varies the duration of exposure, making it difficult to attribute temperature changes specifically to the radiation. Choice C introduces the factor of different cell phone brands, which could introduce variability not related to radiation. Choice D also varies exposure times and introduces the factor of multiple phone brands, making it harder to determine the direct impact of cell phone radiation on water temperature. Therefore, choice A is the most suitable option for this experiment.
Question 2
What is the term for the breakdown of glycogen into glucose subunits?
A. Hydrolysis
B. Reduction
C. Metabolism
D. Transpiration
Show answer and rationale
Correct answer: A — Hydrolysis
Hydrolysis is the term used to describe the breakdown of large molecules into smaller units by adding water. In the case of glycogen being broken down into glucose subunits, this process involves the addition of water molecules to break the glycosidic bonds between glucose molecules, resulting in the release of individual glucose subunits. This process is crucial for providing cells with a source of energy when needed.
Choice B, Reduction, refers to a chemical reaction involving a gain of electrons or a decrease in oxidation state, not the breakdown of glycogen into glucose subunits. Choice C, Metabolism, is a broad term encompassing all biochemical processes in an organism, including anabolism and catabolism, but does not specifically describe the breakdown of glycogen into glucose subunits. Choice D, Transpiration, is the process of water movement through a plant and is not related to the breakdown of glycogen into glucose subunits.
Question 3
How should a researcher test the hypothesis that practicing yoga reduces blood pressure?
A. Record the blood pressure of one male and one female participant before and after participating in a yoga class.
B. Divide 30 female participants into two groups with similar average blood pressure; test each participant's blood pressure after participating in a yoga class.
C. Divide 30 female participants into two groups with similar average blood pressure; have one group watch television for an hour while the other takes a yoga class, record each participant's blood pressure after the hour. Repeat daily for two weeks.
D. Start with 15 men and 15 women; have the men watch television for an hour while the women take a yoga class, record each participant's blood pressure after the hour. Reverse, having the men take a yoga class while the women watch television.
Show answer and rationale
Correct answer: B — Divide 30 female participants into two groups with similar average blood pressure; test each participant's blood pressure after participating in a yoga class.
Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.
Question 4
Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
A. Both daughters will carry the disease.
B. Both sons will carry the disease.
C. One daughter may have the disease.
D. One son may have the disease.
Show answer and rationale
Correct answer: C — One daughter may have the disease.
Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
Question 5
How does asexual reproduction differ from sexual reproduction?
A. asexual reproduction results in all cells being identical to the original cell; sexual reproduction results in half of the cells being identical to the original cell
B. asexual reproduction results in two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
C. sexual reproduction involves two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
D. sexual reproduction involves one cell that yields all cells produced to be identical
Show answer and rationale
Correct answer: C — sexual reproduction involves two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
Sexual reproduction involves two cells (gametes) that contribute genetic material to daughter cells, resulting in significantly greater genetic variation in the offspring. This genetic variation is essential for evolution and adaptation to environmental changes. In contrast, asexual reproduction involves one cell dividing to produce offspring that are genetically identical to the parent cell. Choice A is incorrect because sexual reproduction does not result in half of the cells being identical to the original cell; it involves two cells contributing genetic material. Choice B is incorrect because asexual reproduction does not result in significantly greater variation; it produces genetically identical offspring. Choice D is incorrect because sexual reproduction involves two cells contributing genetic material, not one cell yielding all identical cells.
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Question 6
What is another name for the light-independent reaction in plants?
A. Photosynthesis
B. Calvin cycle
C. Germination
D. Phosphorus cycle
Correct answer:
The light-independent reaction in plants is also known as the Calvin cycle. This biochemical pathway, named after Melvin Calvin who discovered it, takes place in the stroma of chloroplasts and is responsible for converting carbon dioxide into glucose using ATP and NADPH generated during the light-dependent reactions of photosynthesis. The Calvin cycle does not directly require light to function, hence the alternative name as the light-independent reaction. Choices A, C, and D are incorrect. Photosynthesis is the overall process of converting light energy into chemical energy, which includes both light-dependent and light-independent reactions. Germination is the process where a seed sprouts into a new plant. The phosphorus cycle is the biogeochemical cycle that describes the movement of phosphorus through the lithosphere, hydrosphere, and biosphere.
Three students measured the mass of a product of combustion. They recorded measurements of 14 g, 16 g, and 17 g. If the known mass of the product is 30 g, how would you describe the students' measurements?
A. Accurate
B. Precise
C. Both accurate and precise
D. Neither accurate nor precise
Correct answer:
The students' measurements are precise because they are consistently close to each other. However, they are not accurate because all the measurements deviate from the known mass of the product (30 g). Accuracy refers to how close a measurement is to the true or accepted value, while precision refers to the level of agreement among repeated measurements. Since the students' measurements are consistent but do not align with the true value, they can be considered precise but not accurate. Choice A is incorrect because accuracy relates to the proximity of the measurements to the true value, which is not the case here. Choice C is incorrect because although the measurements are precise, they are not accurate. Choice D is incorrect because the measurements are precise as they show good agreement with each other, even though they are not accurate.
The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA).
Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
Cells that line the inner or outer surfaces of organs or body cavities are often linked together by intimate physical connections. These connections are referred to as ______.
A. Separate desmosomes
B. Ronofilaments
C. Tight junctions
D. Fascia adherens
Correct answer:
The correct answer is C: Tight junctions. Tight junctions, also known as zonula occludens, are the intimate physical connections between cells that line the inner or outer surfaces of organs or body cavities. These junctions form a virtually impermeable barrier to fluid, creating a tight seal between the cells. This helps in maintaining the integrity and function of the tissue as well as regulating the movement of substances across the cell layer. Choice A, Separate desmosomes, are cell structures that provide strong adhesion between cells but do not create a barrier to fluid. Choice B, Ronofilaments, is not a term used to describe the connections between cells. Choice D, Fascia adherens, are another type of cell junction involved in cell adhesion, but they are different from tight junctions in terms of their structure and function.
When plants do not receive enough water, their photosynthetic rate drops. This is because:
A. water is a raw material for the light reactions in photosynthesis
B. carbon dioxide is not available
C. water provides the carbon atoms used to make sugar
D. not enough oxygen is produced to keep fermentation running
Correct answer:
When plants do not receive enough water, their photosynthetic rate drops because water is a raw material required for the light reactions in photosynthesis. In the light reactions, water is split to provide electrons, which are then utilized to produce energy carriers used in converting carbon dioxide into glucose during the Calvin cycle. Therefore, without sufficient water, the light reactions cannot proceed effectively, ultimately leading to a decrease in photosynthetic rate. Choice B is incorrect because carbon dioxide is a separate raw material needed for the Calvin cycle, not the light reactions. Choice C is incorrect as water provides electrons, not carbon atoms, for photosynthesis. Choice D is incorrect because fermentation is not directly related to photosynthesis; oxygen is produced during photosynthesis, not fermentation.
The correct answer is C: "Producers > secondary consumers." Producers, like plants, are the foundation of the energy pyramid, containing the highest energy content in an ecosystem. They convert solar energy into chemical energy through photosynthesis. Secondary consumers, being organisms that feed on other organisms, have lower energy content compared to producers. This hierarchy in energy content is due to the transfer of energy through trophic levels. Choice A is incorrect because decomposers, though essential for nutrient recycling, typically have lower energy content than secondary consumers. Choice B is incorrect because primary consumers, which feed directly on producers, have lower energy content than producers. Choice D is incorrect because secondary consumers have lower energy content compared to primary consumers.
How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer:
Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
A student was asked to count birds in a given location over a 24-hour period. Which count would make their data most valid?
A. Count birds at one feeder every 6 hours.
B. Count birds at three feeders at noon and 6:00 P.M.
C. Count birds at one feeder at noon and 6:00 P.M.
D. Count birds at three feeders every 6 hours.
Correct answer:
Counting birds at one feeder at consistent time intervals (noon and 6:00 P.M.) over a 24-hour period ensures that the data collected are evenly distributed and provide a more accurate representation of the bird population in that location throughout the day. This method allows for observations during different times of the day, capturing potential variations in bird activity and distribution. Choice A is not as effective as it lacks observations at different times of the day, potentially missing variations in bird behavior. Choice B involves multiple locations and times, which could introduce more variables and make it harder to analyze the data accurately. Choice D, counting birds at three feeders every 6 hours, may provide too frequent data points and not cover all significant time intervals for observing bird activity.
In contrast with triglycerides, phospholipids are lacking one of which of the following components?
A. Monosaccharide
B. Glycerol
C. Phosphates
D. Fatty acid
Correct answer:
Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.
Glycolysis is the first step in cellular respiration and can occur in both aerobic (presence of oxygen) and anaerobic (absence of oxygen) conditions. In aerobic respiration, glycolysis takes place in the presence of oxygen and continues with the Krebs cycle and the electron transport chain. So, glycolysis does not require the absence of oxygen but can occur in its presence as part of the overall process of aerobic respiration. Choice A is incorrect because glycolysis can occur in the presence of oxygen. Choice C is incorrect because glycolysis is not the final step of fermentation; it is the initial step. Choice D is incorrect because glycolysis is not the final step of anaerobic respiration; it is the first step, followed by further processes to complete anaerobic respiration.
HESI A2 biology practice questions for nursing students in the United States. Fifteen items. Five include answers and rationales in American English.
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